Details

Basic Information
Taxanomy
Sequence Information
Modeled Structures
Gene Information
Gene Ontology
Family Classification

Details : E2QRS1

dbSWEET id: dbswt_1158

Accession:   E2QRS1

Uniprot status:   Unreviewed

Organism:   Canis lupus

Kingdom:   Metazoa

Taxonomy back to top


Eukaryota ⇒ Metazoa ⇒ Chordata ⇒ Craniata ⇒ Vertebrata ⇒ Euteleostomi ⇒ Mammalia ⇒ Eutheria ⇒ Laurasiatheria ⇒ Carnivora ⇒ Caniformia ⇒ Canidae ⇒ Canis.

Sequence Information back to top


Sequence length:   221

Substrate Binding Site:   NNWN           CVV:   451       CHI:   -11.4

Selectivity Filter:   MNMT           CVV:   437       CHI:   -0.4

Fasta sequence:

>tr|E2QRS1|E2QRS1_CANLF|Unreviewed|Canis_lupus|221
MEPGGVADSLLSGACVLFTLAMYSTGLSDLRHMRMTRSVDNVQFLPFLTTDINNLSWLSY
GALKGDGILIFVNATGAVLQTLYILVYVHYCPRKRPVLLQTATLVGVLLLGFGYFWLLVP
NLETQLQQLGLFCSGFTISMYLSPLADLAKIIQMKSTQRLSFPLTIATLLTSASWTLYGF
QLGDPYIMVPNLPGILTSLVRLWLFWKYSQGPDRNYQLLQT

Snake diagram with key positions labelled



Modeled Structuresback to top


Model start:   1     Model end:   210

Alignment file: E2QRS1.pir

Inward Open:

Template:   5CTG.pdb

Model structure:  E2QRS1_inward.pdb

Procheck score ⇒ Ramachandran plot: 90.6% favored    7.2% allowed    1.1% week    1.1% disallowed

Outward Open:

Template:   5CTG_outward.pdb

Model structure:  E2QRS1_outward.pdb

Procheck score ⇒ Ramachandran plot: 91.2% favored    8.3% allowed    .6% week    .0% disallowed

Occluded:

Template:   5CTG_occluded.pdb

Model structure:  E2QRS1_occluded.pdb

Procheck score ⇒ Ramachandran plot: 91.2% favored    6.1% allowed    1.7% week    1.1% disallowed

Gene Informationback to top


Gene ID:   480132     Total Exons:   6     Coding Exons:   6

The diagram below shows the position of Exon-junctions in the protein structure ( Loops and transmembrane helices ).

If more than 1 exon translates a single secondary-structure , only the final exon is represented in figure.
Point on the red bars to view exon number

Gene Ontologyback to top


GO:0005794 - Golgi apparatus

GO:0016021 - integral component of membrane

GO:0005886 - plasma membrane

GO:0042947 - glucoside transmembrane transporter activity

GO:0051119 - sugar transmembrane transporter activity

GO:0008643 - carbohydrate transport

GO:0045815 - positive regulation of gene expression epigenetic

Family Classificationback to top


Pfam:   PF03083: MtN3_slv 

Interpro:   IPR004316: SWEET_sugar_transpr. 

Panther:   NA

Bioinformatics and Biomolecular Simulation Laboratory, Department of Biological Sciences and Bioengineering, IIT Kanpur