Details

Basic Information
Taxanomy
Sequence Information
Modeled Structures
Gene Information
Gene Ontology
Family Classification

Details : E1G905

dbSWEET id: dbswt_1154

Accession:   E1G905

Uniprot status:   Unreviewed

Organism:   Loa loa

Kingdom:   Metazoa

Taxonomy back to top


Eukaryota ⇒ Metazoa ⇒ Ecdysozoa ⇒ Nematoda ⇒ Chromadorea ⇒ Spirurida ⇒ Filarioidea ⇒ Onchocercidae ⇒ Loa.

Sequence Information back to top


Sequence length:   223

Substrate Binding Site:   MNWN           CVV:   479       CHI:   -6

Selectivity Filter:   FMSL           CVV:   456       CHI:   7.7

Fasta sequence:

>tr|E1G905|E1G905_LOALO|Unreviewed|Loa_loa|223
MVALLSIFAIWLTFFSICFTFLPMLQVLDWRKRGTADGFSSINLVLPVLMMGCWLRHGYM
TNDFTNIFINTINLIVFAGYILAFAFYQPCRRYLCLQLFALFFTLFCIFSYVSWQPNDIA
SDVMGSIAAAMQIISLGGQIYEIKRATSFGHTEFIPAELQFGIFFLTIQWTVFGILIENY
YIAIANFAGLLVNIATISLYFIYPPLTWKVPIIGTGPQQEKTE

Snake diagram with key positions labelled



Modeled Structuresback to top


Model start:   1     Model end:   205

Alignment file: E1G905.pir

Inward Open:

Template:   5CTG.pdb

Model structure:  E1G905_inward.pdb

Procheck score ⇒ Ramachandran plot: 89.7% favored    8.6% allowed    .5% week    1.1% disallowed

Outward Open:

Template:   5CTG_outward.pdb

Model structure:  E1G905_outward.pdb

Procheck score ⇒ Ramachandran plot: 92.4% favored    7.0% allowed    .5% week    .0% disallowed

Occluded:

Template:   5CTG_occluded.pdb

Model structure:  E1G905_occluded.pdb

Procheck score ⇒ Ramachandran plot: 91.4% favored    5.9% allowed    1.6% week    1.1% disallowed

Gene Informationback to top


Gene ID:   9947081     Total Exons:   6     Coding Exons:   6

The diagram below shows the position of Exon-junctions in the protein structure ( Loops and transmembrane helices ).

If more than 1 exon translates a single secondary-structure , only the final exon is represented in figure.
Point on the red bars to view exon number

Gene Ontologyback to top


GO:0016021 - integral component of membrane

GO:0005886 - plasma membrane

GO:0008643 - carbohydrate transport

Family Classificationback to top


Pfam:   PF03083: MtN3_slv 

Interpro:   IPR004316: SWEET_sugar_transpr. 

Panther:   NA

Bioinformatics and Biomolecular Simulation Laboratory, Department of Biological Sciences and Bioengineering, IIT Kanpur