MIPModDB
 
STRUCTURE BASED ALIGNMENT
  A conserved positions at helix-helix interface     A Ar/R selectivity filter

Protein
Helix 1
Helix 2
1J4N
FWRAVVAEFLAMILFIFISIGSALGF
DNVKVSLAFGLSIATLAQSVGH
1FX8
LKGQCIAEFLGTGLLIFFGVGCVAAL
GQWEISVIWGLGVAMAIYLTAG
1RC2
MFRKLAAECFGTFWLVFGGCGSAVLA
GFAGVALAFGLTVLTMAFAVGH
1Z98
FWRAAIAEFIATLLFLYITVATVIGH
GLLGIAWAFGGMIFVLVYCTAG
2B60
FWRAIFAEFFATLFYVFFGLGASLRW
HVLQVALAFGLALATLVQAVGH
2F2B
LTKRCIAEFIGTFILVFFGAGSAAVT
DWVAIGLAFGFAIAASIYALGN
ZEMAYS0262FIQKIIAEIFGTYFLMFAGCGAVTINTFPGVAVAWGAAVMAMVYAVGH
ZEMAYS0263LLKKVVSEVVSTFLLVFVTCGAAGIYMFPGICVVWGLVVTVLVYSVGH
ZEMAYS0264LGKKVISEVVATFLLVFVTCGAASIYSQLGQSIAGGLIVTVMIYAVGH
ZEMAYS0265LTRKLGAEFVGTFILIFFATAAPIVNSQLGQSVVGGLIVTVMIYATGH
ZEMAYS0266FYRPGIAEFVATFLFLYISILTVMGVSPFGNAACAGLAVTTIILSTGH
ZEMAYS0267FYRAGIAEFVATFLFLYITILTVMGVSLLGIATSAGLAVTVLVLSLIH
ZEMAYS0268FYRAGIAEFVATFLFLYITVLTVMGVTLLGIATSAGLAVTVLVLSLIH
ZEMAYS0269FYRAGIAEFVATFLFLYITVLTVMGVGLVGVAASIGLAVAVLVMSLAH
ZEMAYS0270FYRAGIAEFVATFLFLYISILTVMGVTLVGVAASAGLAVVAVVLSVVH
ZEMAYS0271FYRAGIAEFVATFLFLYVTVLTVMGVGTLTFPMVCLVVAMTVAFVLSW
ZEMAYS0272LYRAVIAEFIATLLFLYITVATVIGYTFPGVAIVWGLAVMVMVYAVGH
ZEMAYS0273LYRAVIAEFIATLLFLYVTVATVIGYSQLGQSVAGGLIVTVMIYAVGH
ZEMAYS0274LYRAVIAEFIATLLFLYITVATVIGYSQLGQSVAGGLIVTVMIYATGH
ZEMAYS0275LYRAVIAEFIATLLFLYITVATVIGYSPFGNAACAGLAVATVILSTGH
ZEMAYS0276LYRAVIAEFVATLLFLYITVATVIGYTLPGIAIVWGLTIMVLIYSLGH
ZEMAYS0277LYRAVIAEFVATLLFLYITVATVIGYTLPGIAIVWGLTVMVLVYSLGH
ZEMAYS0278LYRAAIAEFIATLLFLYITVLTIIGYTLVGIAVVWGIVIMVLVYCLGH
ZEMAYS0279TVRAAAADAVVTFLWVLCASALGASTTLPGIALVWGLVVTVMIYSIGH
ZEMAYS0280ALRAAAADAVVTFLWVLCVSTLGASTTFPGICVTWGLIVMVMIYSTGH
ZEMAYS0281RPWLVVGDLALAAAWVCAGALVKLLVTFPGICVTWGLIVMVMIYSTGH
ZEMAYS0282ALKAAFAEFISTLIFVFAGQGSGMAFTLIGNAACAGLAVMIIILSTGH
ZEMAYS0283TAKAAVAEFISTLIFVFAGSGSGMAFTLIGCAASAGLAVMIVILSTGH
ZEMAYS0284SIKAYVAEFIATLLFVFAGVGSAIAYGLLEYAVTAGLSVVVVVYSIGH
ZEMAYS0285SIKAYVAEFIATLLFVFAGVGSAIAFALLVTVSLLSVLLFAFNLLCDA
ZEMAYS0286SLKAYVAEFIATLLFVFAGVGSAIAYADAVKVALSLVYMFFFAWLEGF
ZEMAYS0287TIRAAISEFIATAIFVFAAEGSVLSLALLVTTSLLSVLLFTFDLLCGA
ZEMAYS0288CVRAVLAELVLTFLFVFTGVSAAMAAALLVTVSLLSVLLFVFNILCDA
ZEMAYS0289CVRAVLAELVLTFLFVFTGVSASMAAAEAVKVSLSLVYMFLFAWLEAA
ZEMAYS0290FFRGVLGELVLTFLFVFIGVGAAMTDPLVILTSLIFVYVSIFTVIF--
ZEMAYS0291CVRAVLAELILTFLFVFAGVGSAMATPLVISTLVVFVSISIFTVIGNV
ZEMAYS0292SLRSYLAEFISTFLFVFTAVGSAISAGEIVRYLFSIISMFIFAYLQQA

Protein
Helix 3
Helix 4
1J4N
SVLRAIMYIIAQCVGAIVATAILSG
SGQGLGIEIIGTLQLVLCVLATT
1FX8
DKRKVIPFIVSQVAGAFCAAALVYG
FVQAFAVEMVITAILMGLILALT
1RC2
PAKEVVGYVIAQVVGGIVAAALLYL
MLSALVVELVLSAGFLLVIHGAT
1Z98
SLLRALVYMIAQCLGAICGVGLVKA
KGTALGAEIIGTFVLVYTVFSAT
2B60
SLLRAICYVVAQLLGAVAGAAVLYS
VGQATIVEIFLTLQFVLCIFATY
2F2B
PGREVVPYIIAQLLGAAFGSFIFLQ
YWQAMLAEVVGTFLLMITIMGIA
ZEMAYS0262PWRQLPAYVLAQMLGATLASGTLRLEVQSLVIEIITTFYLMFVISGVA
ZEMAYS0263PWIQVPFYWAAQFTGSICASFVLKAHWHSLVIEIIVTFNMMFVTLAVA
ZEMAYS0264PWIQVPFYWAAQFTGAMCAAFVLKAHWHALLIEIVVTFNMMFVTCAVA
ZEMAYS0265PWLQVPAYVAVQALASVCAAFALKGTAQAFFTEFIISFNLLFVVTAVA
ZEMAYS0266SLTRAVFYIIMQCLGAICGRGVVKGKGDGLGAEIVGTFILVYTVFSAT
ZEMAYS0267SLTRALFYIIMQCLGAVCGAGVVKGKGDGLGAEIVGTFILVYTVFSAT
ZEMAYS0268SLTRAIFYIIMQCLGAICGAGVVKGKGDGLGAEIVGTFILVYTVFSAT
ZEMAYS0269SLTRAIFYIIMQCLGAICGAGVVKGKGDGLGAEIVGTFILVYTVFSAT
ZEMAYS0270SLTRALFYMVMQCLGAICGAGVVKGKGDGLGAEIVGTFVLVYTVFSAT
ZEMAYS0271SLTRAVYYVVMQCLGAVCGAGVVKAKGDGLGAEVVGTFVLVYTVFSAT
ZEMAYS0272SLVRALLYIVAQCLGAICGVGLVKARGTGLGAEIIGTFVLVYTVFSAT
ZEMAYS0273SLVRALLYMVAQCLGAVCGVGLVKARGAGLGAEIVGTFVLVYTVFSAT
ZEMAYS0274SLVRALLYIIAQCLGAICGVGLVKGKGTGLAAEIIGTFVLVYTVFSAT
ZEMAYS0275SLVRALLYIIAQCLGAICGVGLVKGKGTGLAAEIIGTFVLVYTVFSAT
ZEMAYS0276SLVRALLYIVAQCLGAICGVGLVKGKGTGLAAEIIGTFVLVYTVFSAT
ZEMAYS0277SLVRALLYMAAQSLGAICGVALVKGTGTGLAAEIIGTFVLVYTVFSAT
ZEMAYS0278SLVRALLYMIAQCAGAICGAGLAKGKGTALGAEIIGTFVLVYTVFSAT
ZEMAYS0279SLFSVALRFPAQAAGAVGGALAISEPHTGALAEGVLTFVITLTVLWVI
ZEMAYS0280SLFSIALRLPAQAAGAVGGALAISEPHTGAGAELVLTFVITLAVLLII
ZEMAYS0281YLFTAFARIPAQVIGAVLGVKLIQVAHHGALAEGLATFMVVMVSVTLK
ZEMAYS0282TLFRGLLYWVAQLLGSTVACFLLRFVWEALVLEIVMTFGLVYTVYATA
ZEMAYS0283SLLKALVYWVAQLLGSVVACLLLKIAMNAVVLEMVMTFGLVYTVYATA
ZEMAYS0284TILTGVFYWVAQLLGATVACLLLGFELEGVVFEVVITFALVYTVYATA
ZEMAYS0285TVLTGLFYWVAQLLGASVACLLLRFELEGVVFEIVITFALVYTVYATA
ZEMAYS0286TILTGILYWVAQLLGASVACFLLQYEIEGVVMEIVITFALVYTVYATA
ZEMAYS0287SLVRAVLYWVAQLLGAVAATLLLRLDWHAVLLEAVMTFGLMYAYYATV
ZEMAYS0288TKLRAVLYVAAQLLASSAACVLLRFPMQGLVMEVILTFSLLFVTYAMI
ZEMAYS0289TKLRALLYVAAQLLASSLACILLRYPMQGLVMEVILTFSLLFVTYAMI
ZEMAYS0290TLFRSSLYIAAQMLASSAACFLLRWPLQGVVAEAVFTFSLLFVIYATI
ZEMAYS0291TLFRSALYVAAQLLGSTLACLLLAFALRGVLMEAVLTFSLLFAVYATV
ZEMAYS0292GVPSAMFYWASQLLGATFACLSLNLGFGGAVLEGVLTFLLVYTVHVVG

Protein
Helix 5
Helix 6
1J4N
SGPLAIGFSVALGHLLAID
WIFWVGPFIGAALAVLIYDFI
1FX8
LAPLLIGLLIAVIGASMGP
LVPLFGPIVGAIVGAFAYRKL
1RC2
FAPIAIGLALTLIHLISIP
WFFWVVPIVGGIIGGLIYRTL
1Z98
LAPLPIGFAVFMVHLATIP
WIFWVGPFIGAAVAAAYHQYV
2B60
SVALAVGFSLTLGHLFGMY
WVYWVGPVIGAGLGSLLYDFL
2F2B
FAGIIIGLTVAGIITTLGN
SIYVIGPIVGAVLAALTYQYL
ZEMAYS0262LAGLAVGATILLNVLIAGPWVYVVGPVVGAVAGAWAYNLI
ZEMAYS0263LAGLAVGSAVCITSIFAGAWIYFLGPVLGTLSGAWTYTYI
ZEMAYS0264LAGLAVGSAVCITSIFAGPWIYFLGPVIGTLSGAWVYTYI
ZEMAYS0265LAGIAVGAAVTLNILVAGPWIYLLAPTLGALAAASVYKAV
ZEMAYS0266LAPLPIGFAVFLVHLATMGWIFWVGPFIGAALAAIYHQVI
ZEMAYS0267LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAAIYHQVI
ZEMAYS0268LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAAIYHQVI
ZEMAYS0269LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAAIYHQVI
ZEMAYS0270LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAAIYHVVI
ZEMAYS0271LAPLPIGFAVFLVHLATIPWIFWVGPFAGAALAAVYHQVV
ZEMAYS0272LAPLPIGFAVFMVHLATIPWIFWVGPLVGAAIAAFYHQYI
ZEMAYS0273LAPLPIGFAVFMVHLATIPWIFWVGPLLGAAIAAFYHQYI
ZEMAYS0274LAPLPIGFAVFMVHLATIPWIFWVGPLIGAAIAAAYHQYV
ZEMAYS0275LAPLPIGFAVFMVHLATIPWIFWVGPLIGAAIAAAYHQYV
ZEMAYS0276LAPLPIGFAVFMVHLATIPWIFWVGPFIGAAIAAAYHQYV
ZEMAYS0277LAPLPIGFAVFMVHLATIPWIFWVGPFIGAAIAALYHQIV
ZEMAYS0278LAPLPIGFAVFMVHLATIPWIYWVGPFVGAAVAAIYHQYI
ZEMAYS0279LKTLLLSTSIVSVILAGAEYVYWICPFIGAMLAGWIFRVV
ZEMAYS0280IKTWMISICTLCLVLSGAAYVYWICPFIGAILGAWIFRAM
ZEMAYS0281MKTWITSIWKNTIHLLSSDLVYWLAPLQATLLAVWAVTFF
ZEMAYS0282IAPIAIGFIVGANILVGGAWVYWVGPLIGGGLAGVIYELL
ZEMAYS0283IAPIAIGFIVGANILAGGAWVYWVGPLAGAAIAALVYDII
ZEMAYS0284IAPIAIGFIVGANILAAGPWVYWVGPLVGGGLAGLVYGDV
ZEMAYS0285IAPIAIGFIVGANILAAGPWVYWVGPLIGGGLAGLVYGDV
ZEMAYS0286IAPMAIGFIVGANILAAGPWVYWVGPLVGGGLAGLVYGDV
ZEMAYS0287IAPLAVGFLLGANVLAGGPWVYWLGPFLGAGLAGLVYEYL
ZEMAYS0288IGPLLTGLIVGANSLAGGNWVYWIGPLLGGPLAGFVYESL
ZEMAYS0289IGPLLTGLIVGANSLAGGNWVYWIGPLLGGSLAGFVYESL
ZEMAYS0290AGPLLTGLLVGANSVAGAAWVYWVGPLAGGPLAVLVYECC
ZEMAYS0291MGPLLVGLVVGANVLAGGPWVYWVGPLIGGPLAGLVYDGL
ZEMAYS0292LGALAVGLTQGAFVLAAGAAVYWAGPMVGAAVAALVYQIM

Protein
Loop B
Loop E
1J4N
AHLNPAVTLGLLLS
GCGINPARSFGSSVIT
1FX8
AHLNPAVTIALWLF
GFAMNPARDFGPKVFA
1RC2
GHFNPAVTIGLWAG
NTSVNPARSTAVAI-F
1Z98
GHINPAVTFGLFLA
GTGINPARSFGAAVIF
2B60
AHVNPAVTFAFLVG
GAGMNPARSFAPAILT
2F2B
CHINPAVTIGLWSV
GSSLNPARTFGPYLND
ZEMAYS0262AHFNPAVTLAFATSGASMNPARSVGPALVS
ZEMAYS0263AHMNPAVTLAFAVFGGSMNPARTLGPALAS
ZEMAYS0264AHMNPAVTLSFACFGGSMNPARTLAPAVAS
ZEMAYS0265AHLNPSLTIAFAALGGSMNPVRTLGPAVAA
ZEMAYS0266-HINPAVTFGLFLAGTGINPARSLGAAVIY
ZEMAYS0267GHINPAVTFGLFLAGTGINPARSLGAAIIY
ZEMAYS0268GHINPAVTFGLFLAGTGINPARSLGAAIIY
ZEMAYS0269GHINPAVTFGLFLAGTGINPARSLGAAIIY
ZEMAYS0270GHINPAVTFGLFLAGTGINPARSLGAAIVY
ZEMAYS0271GHINPAVTFGLLLAGTGINPARSLGAAIIY
ZEMAYS0272GHINPAVTFGLFLAGTGINPARSLGAAVIY
ZEMAYS0273GHINPAVTFGLFLAGTGINPARSLGAAVVY
ZEMAYS0274GHINPAVTFGLFLAGTGINPARSLGAAVIY
ZEMAYS0275GHINPAVTFGLFLAGTGINPARSLGAAVIY
ZEMAYS0276GHINPAVTFGLFLAGTGINPARSLGAAVIY
ZEMAYS0277GHINPAVTFGLFLAGTGINPARSLGAAVVY
ZEMAYS0278GHINPAVTFGLFLGGTGINPARSFGPAVIF
ZEMAYS0279ASFNPTDFAASYAAGPSMNPANAFGWAYVN
ZEMAYS0280ASFNPTGVAAFYAAGPSMNPANAFGWAYVN
ZEMAYS0281ASYNPLTVLAAALAGGIMNPASAFAWAYAR
ZEMAYS0282GHVNPAVTFGAFVGGASMNPAVSFGPALVS
ZEMAYS0283GHVNPAVTFGAFVGGASMNPAVSFGPAVVT
ZEMAYS0284GHLNPAVTFGLAVGGGSMNPARSFGPAVAA
ZEMAYS0285GHLNPAVTFGLAVGGGSMNPARSFGPAVAA
ZEMAYS0286GHLNPAVTFGLAVGGGSMNPARSFGPAVAA
ZEMAYS0287GHVNPAVTFGALVGGAGMNPARVFGPALVG
ZEMAYS0288GHLNPAVTVGLMVRGASMNPARSFGPALAT
ZEMAYS0289GHLNPAVTVGILVRGASMNPARSFGPAMAT
ZEMAYS0290GHVNPAVTLSLAVGGASMNPARSFGPAVAS
ZEMAYS0291GHINPAVTLGLAATGASMNPARSFGPALVA
ZEMAYS0292GHVNPAVTFAYAIGGASMNPARSFGPAVVS
 
 
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Bioinformatics and Biomolecular Simulation Laboratory, Department of Biological Sciences and Bioengineering,
Indian Institute of Technology, Kanpur, INDIA-208016
Copyright (c) 2007 All rights reserved, IIT Kanpur