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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| STPYOG0695 | WTVKYITEFIATAFLVILGNGAVANV | GWLVIAFGYGLGVMMPALMFGN | | STPYOG0696 | ~-MDIFGEFLGTVLLVLLGNGVVAGV | GWIVIASGWGIAVAVAVFISGK | | STPYOG0699 | WTVKYITEFIATAFLIILGNGAVANV | GWLVIAFGYGLGVMMPALMFGN | | STPYOG0700 | ~-MDIFGEFWDTALLVLLGNGVVAGV | GWIVIATGWGIAVAVAVFISGK | | STPYOG0701 | ~-MNFIGELLGTFILVLLGDGVVSAC | GWIAIVLGWGIAVTVAVYISGF | | STPYOG0741 | WTVKYITEFIATAFLIILGNGAVANV | GWLVIAFGYGLGVMMPALMFGN | | STPYOG0742 | ~-MDIFGEFLGTALLVLLGNGVVAGV | GWIVIATGWGIAVAVAVFISGK |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| STPYOG0695 | PWAHVLQYVVAQLLGAIFGQLVVVM | YINGFLNEFVGSFVLFFGALALT | | STPYOG0696 | AWSTAIAYSLAQLLGAMLGSTLVFL | TSSNLLSEIFGTFVLMLGILAFG | | STPYOG0699 | PWAHVLQYVVAQLLGAIFGQLVVVM | YINGFLNEFVGSFVLFFGALALT | | STPYOG0700 | AWSTAIAYSLAQLLGAMVGSTLVFL | TSSNLLSEIFGTFVLMLGILAFG | | STPYOG0701 | PWSQVVTYLVAQFLGAMLGALVLYL | TWSNLFGEALGTAVLVITVMAIG | | STPYOG0741 | PWAHVLQYVVAQLLGAIFGQLVVVM | YINGFLNEFVGSFVLFFGALALT | | STPYOG0742 | AWSTAIAYSLAQLLGAMVGSTLVFL | TSSNLLSEIFGTFVLMLGILAFG |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
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| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| STPYOG0695 | VAHIGIGFLVMVLVTSLGG | WVPVVAPILAAIVAVAAFKYL | | STPYOG0696 | LGTLCVGTLVIGIGLSLGG | WIPVVGPIIGAALAVLLFQVM | | STPYOG0699 | VAHIGIGFLVMVLVTSLGG | WVPVVAPILAAIVAVAAFKYL | | STPYOG0700 | LGTLCVGTLVIGIGLSLGG | WIPVVGPIIGVALAVLLFQVM | | STPYOG0701 | FGPIIVGFVVMAVGFSLGA | WIPVLGPILGGVAGALIYQAI | | STPYOG0741 | VAHIGIGFLVMVLVTSLGG | WVPVVAPILAAIVAVAAFKYL | | STPYOG0742 | LGTLCVGTLVIGIGLSLGG | WIPVVGPIIGAVLAVLLFQVM |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| STPYOG0695 | NHINPAFTVGLAVS | GPALNPARDFGPRLLH | | STPYOG0696 | AHLNPAVSLAFAMS | GYAINPARDLGPRLVH | | STPYOG0699 | NHINPAFTVGLAVS | GPALNPARDFGPRLLH | | STPYOG0700 | AHLNPAVSLAFAMS | GYAINPARDLGPRLVH | | STPYOG0701 | AHLNPAVTLAMAAI | GYAINPARDLGPRIMH | | STPYOG0741 | NHINPAFTVGLAVS | GPALNPARDFGPRLLH | | STPYOG0742 | AHLNPAVSLAFAMS | GYAINPARDLGPRLVH |
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