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STRUCTURE BASED ALIGNMENT |
| |
A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| SATYhi0727 | LKGQCIAEFLGTGLLIFFGVGCVAAL | GQWEISVIWGLGVAMAIYLTAG | | SATYhi0728 | LKAQCGAEFLGTGLFLFFGIGCLSAL | GLWEICIIWGLGISLAVYLTAG | | SATYPH0631 | LKAQCGAEFLGTGLFLFFGIGCLSAL | GLWEICIIWGLGISLAVYLTAG | | SATYPH0730 | LKGQCIAEFLGTGLLIFFGVGCVAAL | GQWEISVIWGLGVAMAIYLTAG |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
|
| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| SATYhi0727 | DKRKVVPFIISQVAGAFCAAALVYG | FVQAFAVEMVITAILMGLILALT | | SATYhi0728 | PKQKVLPYIIAQFAGAFGGDLLAYV | VWQAALVEVVITSILMGMIMALT | | SATYPH0631 | PKQKVLPYIIAQFAGAFGGALLAYV | VWQAALVEVVITSILMGMIMALT | | SATYPH0730 | DKRKVVPFIISQVAGAFCAAALVYG | FVQAFAVEMVITAILMGLILALT |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
|
WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| SATYhi0727 | LAPLLIGLLIAVIGASMGP | LVPLFGPIVGAILGAFAYRKF | | SATYhi0728 | LAPLLIGILVAVIGASTGP | IVPIVAPVIGACAGAAIYRYF | | SATYPH0631 | LAPLLIGILVAVIGASTGP | IVPIVAPVIGACAGAAIYRYF | | SATYPH0730 | LAPLLIGLLIAVIGASMGP | LVPLFGPIVGAILGAFAYRKF |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| SATYhi0727 | AHLNPAVTIALWLF | GFAMNPARDFGPKMFA | | SATYhi0728 | GHLNPAVTIALWLF | GFAMNPARDFGPKLFT | | SATYPH0631 | GHLNPAVTIALWLF | GFAMNPARDFGPKLFT | | SATYPH0730 | AHLNPAVTIALWLF | GFAMNPARDFGPKMFA |
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