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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| RASATI0595 | ALRAALAEFISTLIFVFAGSGSGIAF | GLVAAALAHAFGLFVAVSVGAN | | RASATI0622 | FWRAGIAEFIATFLFLYITVLTVMGV | GIQGIAWAFGGMIFALVYCTAG | | RASATI0623 | FYRAVIAEFVATLLFLYITVLTVIGY | GILGIAWAFGGMIFILVYCTAG | | RASATI0626 | SLRAYLAEFISTLLFVFAGVGSAIAY | GLVAIAVCHGFALFVAVAIGAN | | RASATI0782 | LYRAVIAEFVATLLFLYITVLTVIGY | GILGIAWAFGGMIFILVYCTAG | | RASATI0783 | LYRAVIAEFVATLLFLYVTVLTVIGY | GILGISWAFGGMIFILVYCTAG | | RASATI0784 | FWRAGIAEFIATFLFLYITVLTVMGV | GIQGIAWAFGGMIFALVYCTAG |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| RASATI0595 | TLLRGILYWIAQLLGSVVACLLLKF | SLNGFVFEIVMTFGLVYTVYATA | | RASATI0622 | SLTRALYYIVMQCLGAICGAGVVKG | KGSGLGAEIIGTFVLVYTVFSAT | | RASATI0623 | SLVRAILYMVAQCLGAICGVGFVKA | TGTGLAAEIIGTFVLVYTVFSAT | | RASATI0626 | TLITGVFYWVAQLLGSTAACFLLKY | AIEGVVMEIIITFSLVYTVYPTA | | RASATI0782 | SLVRAVLYMVAQCLGAICGVGFVKA | TGTGLAAEIIGTFVLVYTVFSAT | | RASATI0783 | SLVRAVLYMVAQCLGAICGVGFVKA | TGTGLAAEIIGTFVLVYTVFSAT | | RASATI0784 | SLTRAVYYIVMQCLGAICGAGVVKG | KGSGLGAEIIGTFVLVYTVFSAT |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| RASATI0595 | IAPIAIGFIVGANILAGGA | WIYWAGPLVGGGLAGLIYEFV | | RASATI0622 | LAPLPIGFAVFLVHLATIP | WVFWVGPFIGAALAALYHVIV | | RASATI0623 | LAPLPIGFAVFMVHLATIP | WIFWVGPFIGAAIAAFYHQFV | | RASATI0626 | IAPLAIGLIVGANILAAGP | WVYWVGPLIGGGLAGVTYGNV | | RASATI0782 | LAPLPIGFAVFMVHLATIP | WIFWVGPFIGAAIAAFYHQFV | | RASATI0783 | LAPLPIGFAVFMVHLATIP | WIFWVGPFIGAAIAAFYHQFV | | RASATI0784 | LAPLPIGFAVFLVHLATIP | WVFWVGPFIGAALAALYHVIV |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| RASATI0595 | GHVNPAVTFGAFVG | GASMNPAVAFGPAVVS | | RASATI0622 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY | | RASATI0623 | GHINPAVTFGLLLA | GTGINPARSFGAAVIF | | RASATI0626 | GHVNPAVTFGLAVG | GGSMNPARSFGPAVAA | | RASATI0782 | GHINPAVTFGLFLA | GTGINPARSFGAAVIY | | RASATI0783 | GHINPAVTFGLFLA | GTGINPARSFGAAVIY | | RASATI0784 | GHINPAVTFGLFLA | GTGINPARSLGAAIIF |
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