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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| PHNODO0856 | QYPQAPAEFLATFVYLFLGICVNLSV | SFETQAWGWGFAIMIGIYLAGG | | PHNODO0863 | VLREPFAEFWGVAIMVMFGDGSVAQV | PGGNGFGHWALGVMLGIYVAGD | | PHNODO0870 | ELVAAVAEFAGTFMFLFFAFGGTQVA | VLLYISLIFGFSLMVCVWVFFR | | PHNODO0885 | ELTAFIGEFIGTFMFLALAFCGTQIA | KLLYIAFAFGLSLAINVAIFAD |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
|
| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| PHNODO0856 | PWRMAVVYIACQMLAGLCAGALAYG | TASGFFNDFVYMAVWVCTAFALG | | PHNODO0863 | PWRRFPVYFVAQILGGFVGSGIVYA | KASQFFSEFIASALLINNGVPKD | | PHNODO0870 | KWDRAVLCFISQMLAGIAAAGVVSA | PTMGVFLEMFLTSLLVFTIFMLA | | PHNODO0885 | DWRRMVHTIISQMIAGMAASGFIAA | TARGLFLEAFVTSMLILTILMLE |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
|
WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| PHNODO0856 | MTALIFGLNGFLTMVALGY | YGPWGASIAGALFGGLMYDLF | | PHNODO0863 | WFPLCLFFLIFGLGSCFGW | QIPMVAPFLGCAFGAALYDIF | | PHNODO0870 | LAPVGIGLSLFVAEMVGVF | YIYWFGPVMGTLLAFGMYRIV | | PHNODO0885 | AKPMHIGMALFVAELCSAF | WIYWLGPLLGSAVASGAYWLI |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| PHNODO0856 | AHLSPTISLSLTVY | GLGISPARDLGPRLVG | | PHNODO0863 | AYLNPAITFSNCLF | GYAINIARDFGPRLMS | | PHNODO0870 | GLFNPAVTLGLYLI | GGSLNPSRSFGPCVVT | | PHNODO0885 | GKFNPAVSMALFIT | GGSLNPARSFGPCVVV |
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