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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| PEHYBR0712 | ALKAALAEFISTLIFVFAGQGSGMAY | GLISASLAHAFGLFVAVSVGAN | | PEHYBR0713 | FYRALIAEFIATLLFLYITVLTVIGY | GILGIAWAFGGMIFILVYCTAG | | PEHYBR0714 | FYRAVIAEFIATLLFLYVTIATVIGH | GILGIAWAFGGMIFVLVYCTAG | | PEHYBR0715 | FYRALIAEFIATLLFLYVTVATVIGH | GILGIAWAFGGMIFVLVYCTAG | | PEHYBR0716 | FYRAGIAEFMATFLFLYITVLTVMGV | GIQGIAWAFGGMIFALVYCTAG | | PEHYBR0717 | FYRAGIAEFMATFLFLYITILTVMGV | GIQGIAWAFGGMIFALVYCTAG |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| PEHYBR0712 | TFFRGILYIIAQLLGSTAACFILEF | VWNALVFEIVMTFGLVYTVYATA | | PEHYBR0713 | SLIRAVMYMVAQCLGAICGVGLVKA | KSVGLSAEIIGTFVLVYTVFSAT | | PEHYBR0714 | SLIRAVAYIISQCLGAICGVGLVKA | KGTALGAEIIGTFVLVYTVFSAT | | PEHYBR0715 | SLTRAIAYIISQSLGAICGVGLVKA | NGTALGAEIIGTFVLVYTVFSAT | | PEHYBR0716 | SLTRALFYMVMQCLGAICGAGVVKG | KGDGLGAEIVGTFVLVYTVFSAT | | PEHYBR0717 | SLTRALFYIVMQCLGAICGAGVVKG | KGDGLGAEIVGTFVLVYTVFSAT |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| PEHYBR0712 | IAPIAIGFIVGANILAGGA | WIYWAGPIIGGGLAGVVYELL | | PEHYBR0713 | LAPLPIGFAVFMVHLATIP | WIFWVGPFIGAAIAAFYHQFI | | PEHYBR0714 | LAPLPIGFAVFMVHLATIP | WIFWVGPFIGALIAALYHQFV | | PEHYBR0715 | LAPLPIGFAVFMVHLATIP | WIFWVGPFVGALAAAAYHQYI | | PEHYBR0716 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAALYHQVV | | PEHYBR0717 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAVYHQII |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| PEHYBR0712 | GHVNPAVTFGAFIG | GASMNPAVSFGPSLVS | | PEHYBR0713 | GHINPAVTFGLFLA | GTGINPARSLGAAVIF | | PEHYBR0714 | GHINPAVTFGLFLA | GTGINPARSFGAAVIY | | PEHYBR0715 | GHINPAVTFGLFLA | GTGINPARSFGAAVIY | | PEHYBR0716 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY | | PEHYBR0717 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY |
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