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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| NITABA0610 | FYRAGIAEFMATFLFLYITILTVMGL | GIQGVAWAFGGMIFALVYCTAG | | NITABA0655 | HGLFTELEFSMATFLFLYITILTVMG | GIQGVAWAFGGMIFALVYCTAG | | NITABA0720 | FHRALIAEFIATLLFLYVTVATVIGH | GILGISWAFGGMIFVLVYCTAG | | NITABA0721 | FYRAGIAEFMATFLFLYITILTVMGL | GIQGVAWAFGGMIFALVYCTAG | | NITABA0798 | CIQALIVEFICTFLFVFAGVGSAMAA | SLFFVAMAHALVVAVTISAGFR | | NITABA0813 | TLKAALAEFICTLIFVFAGQGSGMAF | GLISASIAHAFGLFVAVSVGAN | | NITABA0819 | SLKAYVAEFIATLLFVFAGVGSAIAY | GLVAVAVAHAFALFVGVSIAAN | | NITABA0820 | SLKAYVAEFIATLLFVFAGVGSAIAY | GLVAVAVAHAFALFVGVSIAAN |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
|
| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| NITABA0610 | SLTRAIFYIVMQCLGAICGAGVVKG | KGDGLGAEIIGTFVLVYTVFSAT | | NITABA0655 | SLTRAVFYMVMQCLGAICGAGVVKG | KGDGLGAEIIGTFVLVYTVFSAT | | NITABA0720 | SLLRAVGYIIAQSLGAICGVGLVKG | KGTALGAEIIGTFVLVYTVFSAT | | NITABA0721 | SLTRAVFYMVMQCLGAICGAGVVKG | KGDGLGAEIIGTFVLVYTVFSAT | | NITABA0798 | TVFRSILYWIDQLLASVAACALLNY | YGQGIIMEVILTFSLLFTVYTTI | | NITABA0813 | TLFRGILYIVAQLLGSTVACFLLEF | VWNAFVFEIVMTFGLVYTVYATA | | NITABA0819 | TILTGFFYWIAQLLGSTVACLLLKY | GLQGVVMEIIITFALVYTVYATA | | NITABA0820 | TILTGFFYWIAQLLGSTVACLLLKY | GFQGVVMEIIITFALVYTVYATA |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
|
WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| NITABA0610 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAVYHQII | | NITABA0655 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAVYHQII | | NITABA0720 | LAPLPIGFAVFMVHLATIP | WIFWVGPFVGALVAAVYHQYI | | NITABA0721 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAVYHQII | | NITABA0798 | MGPLLTGLVVGANIMAGGP | WVYWVGPLIGGGLAGFICENF | | NITABA0813 | IAPIAIGFIVGANILAGGA | WVYWAGPLVGGGIAGVVYELI | | NITABA0819 | IAPIAIGFIVGANILAAGP | WIYWAGPLIGGGLAGFIYGDV | | NITABA0820 | IAPIAIGFIVGANILAAGP | WIYWAGPLIGGGLAGFIYGDV |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| NITABA0610 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY | | NITABA0655 | GHINPAVTFGLFLA | GTGITPARSLGAAIIF | | NITABA0720 | GHINPAVTFGLFLA | GTGINPARTFGAAVIY | | NITABA0721 | GHINPAVTFGLFLA | GTGINPARSLGAAIIF | | NITABA0798 | GHLNPAVTLGLCMG | GASMNPARSFGPAFVS | | NITABA0813 | GHVNPAVTFGAFVG | GASMNPAVSFGPALVS | | NITABA0819 | GHLNPAVTLGLAVG | GGSMNPARSFGPAVVA | | NITABA0820 | GHLNPAVTLGLAVG | GGSMNPARSFGPAVVA |
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