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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| HOVULG0611 | LYRAVIAEFVATLLFLYITVATVIGY | GTLGIAWAFGGMIFVLVYCTAG | | HOVULG0612 | FYRAGIAEFLATFLFLYISVLTVMGV | GIQGIAWSFGGMIFVLVYCTAG | | HOVULG0651 | FYRAGIAEFMATFLFLYVTILTVMGY | GIQGIAWSFGGMIFALVYCTAG | | HOVULG0658 | ALKAALAEFISTLIFVFAGQGSGMAF | GLISAAIAHAFALFVAVSVGAN | | HOVULG0769 | SLRSYFAEFISTFLFVFTAVGSAISA | SLVATAVAQSFGLFAAVFIAAD | | HOVULG0770 | SIRSYVAEFIATLLFVFAGVGSAISY | GLVAIAIAHAFALFVGVAMAAN | | HOVULG0788 | FYRAGIAEFIATFLFLYVTVLTVMGV | GVQGIAWSFGGMIFALVYCTAG |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| HOVULG0611 | SLIRALLYIIAQCLGAICGVGLVKG | KGTGLAAEIIGTFVLVYTVFSAT | | HOVULG0612 | SLTRAVFYIVMQCLGAICGAGVVKG | KGDGLGAEIVGTFVLVYTVFSAT | | HOVULG0651 | SLTRAVFYIIMQCLGAICGAGVVKG | KGSGLGAEIIGTFVLVYTVFSAT | | HOVULG0658 | TLFRGLLYWVAQLLGSTAACFLLRF | AWEAVVLEIVMTFGLVYTVYATA | | HOVULG0769 | GVPTAIFYWTCQLLGSTLACLVLHF | GFGASIVEGVMTFMVVYTVHVAG | | HOVULG0770 | TILTGLFYWVAQLLGASVACLLLQF | EVEGVVMEIVITFALVYTVYATA | | HOVULG0788 | SLTRAIFYIIMQCLGAICGAGVVKG | KGDGLGAEIIGTFVLVYTVFSAT |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
|
WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| HOVULG0611 | LAPLPIGFAVFMVHLATIP | WIFWVGPLIGAAIAAAYHQYV | | HOVULG0612 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAIYHVVV | | HOVULG0651 | LAPLPIGFAVFLVHLATIP | WIFWVGPFIGAALAAIYHQVV | | HOVULG0658 | IAPIAIGFIVGANILVGGA | WVYWVGPLIGGGLAGVIYELL | | HOVULG0769 | LGALVVGLVTGACVLAAGS | AVYWAGPMIGAAVAALVHQNL | | HOVULG0770 | IAPMAIGFIVGANILAAGP | WVYWVGPLIGGGLAGLVYGDV | | HOVULG0788 | LAPLPIGFAVFLVHLATIP | WIFWVGPFVGAALAAVYHQVI |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| HOVULG0611 | GHINPAVTFGLFLA | GTGINPARSLGAAVIY | | HOVULG0612 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY | | HOVULG0651 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY | | HOVULG0658 | GHVNPAVTFGAFVG | GASMNPAVSFGPALVS | | HOVULG0769 | GHVNPAVTFAFAIG | GASMNPARSFGPAVVS | | HOVULG0770 | GHLNPAVTFGLAVG | GGSMNPARSFGPAVAA | | HOVULG0788 | GHINPAVTFGLFLA | GTGINPARSLGAAIIY |
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