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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| GIZEAE0855 | NCQDAFSEFFGTFVLLLFGDGVVAQV | GWGSSLTGLSLGVMLGVYVGGK | | GIZEAE0859 | RHPEPLAEFLATAVAIFLGLTGTLSV | TYETSCWAWGFAWMFGIYLGGG | | GIZEAE0868 | HFVAGVGEFIGTTMFLFFAFAGTEVA | KLLYISIIFGFSLMVNVWVFFR | | GIZEAE0875 | HMVAASGEFVGTFLFLYFGYAGNIVA | TVMYIAMAYGFSLLVNVWTFYR | | GIZEAE0877 | ALVIVLGEFCGTFMFLLLSFIGAQTA | SLMYIAASFGTALAVNVWIFYR |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
|
| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| GIZEAE0855 | PWRKFPIYAVAQVLGAMAAAAVVYG | RTGMFFSEFIASTILQFVIFAMA | | GIZEAE0859 | PWRQCVIYVFVQFIASIVAGALAYA | LKSAFFNQVVGSAIMMIAVFALG | | GIZEAE0868 | SVTRAIVLFLAQILGSMLASVVVRY | LVQGVFIEALLTAELVFTIFMLA | | GIZEAE0875 | PWIRALFLFPSQIIAAMCAGGLVNA | IAQGVFLEMFFTAQLVFVVLMLA | | GIZEAE0877 | TPIHALLIIPTQLVAAITAAGITDA | VAQGVFIEMFLTSQLVLTVYFLA |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
|
WIFWVGPFIGAALAVLIYDFI
|
| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| GIZEAE0855 | LMPLGLFFLIFGIGACFGW | WIPMVAPFFGCAFGGFLYDVF | | GIZEAE0859 | MHALVLGFLVTTLKFTLGY | YGPWAATLIGSLLGCTLYDGF | | GIZEAE0868 | IAPVGIGLALFIAEMVGVQ | WIYWVGPAIGSLIAVCFYWFI | | GIZEAE0875 | LAPVGIGLALFVALIPGVF | WIYWVGPLLGAALAAGYFRLV | | GIZEAE0877 | LAPIGIGISVFIAHICATN | WIYYIGPFMGSLLAFGCYKIF |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| GIZEAE0855 | GHLNPAVTLANCLF | GYAINLARDFGPRLVS | | GIZEAE0859 | AHMNPAISVSLSIF | GSALNPASDFGPRVIA | | GIZEAE0868 | GLFNPAVTMAMLMV | GGSLNPARSFGPCVIT | | GIZEAE0875 | GLFNPAVTFGLCLS | GGSANPVRSFGCAVGS | | GIZEAE0877 | GMFNPAVTLGLVLV | GTSINPARSFGPSVVA |
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