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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| BOFUCK0895 | TMREPFSEFFGVFILILFGDGVVAQV | SYQSISWGWGIGVMLGVYASG- | | BOFUCK0917 | HFVATIGEFVGTTMFLFFAFAGTQVA | VQLYIAVIFGFSLMVNVWIFFR | | BOFUCK0923 | HIVAVIGELIGTSLFLFFGYAGIEVA | VLFYISATFGASLMVTAWIFFR | | BOFUCK0939 | WIREMAAEAMGVFFFVYPGIASCASF | SVFQIGWAFAIGIAFAIITCGS | | BOFUCK0940 | HFIAFLGEFVGTFLFLFFAYGGTQTA | QLLYIALIFGFSLTVNVWIFFR | | BOFUCK0952 | YLVSMIGELVGTFLFLFFAFAAAQTA | KLLYIALAFGASLAANVWVFFR |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| BOFUCK0895 | PWRKFPIYMLAQVLGAMCASGVVYA | KTGQFFSEFVASTILMFCIYALQ | | BOFUCK0917 | PIPRAACLFFAQILGGIAASGMVLG | TVQGVFIEAILTAELVFTIFMLA | | BOFUCK0923 | SPIRAFLLVITQLGASCLAAILVQE | MGQGFVIEAITTAALIFTIIMLA | | BOFUCK0939 | PWKKVPQYIFAQVFGSFMAAMLLVG | YGYLFFIEFFADVFVGIVIWACL | | BOFUCK0940 | GPVRSIFIFIAQVVASIAAAAAVRG | IAQGLFLEMFFTIELVFTILMLA | | BOFUCK0952 | SPTKALILIPAQLVGGSLAAAAVKG | NVQGLFIELLLTFMLVFTILMLV |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
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| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| BOFUCK0895 | LTPLGLFFVIFGIGACFGW | WVPMVAPFIGCLFGGWLYEKG | | BOFUCK0917 | IAPVGIGLALFIAEMVGVY | WIYWIGPITGTFIAVFFYKFI | | BOFUCK0923 | VAPIGIGLALFVAHMVAVP | WIYWVGPILGAGLAVLFFRLI | | BOFUCK0939 | AVPWVIGLGYATMIWGFAD | LIPVLTSIPAMLFGTALYEMI | | BOFUCK0940 | VAPVGIGLSLFVAELMGVA | WIYWLGPLMGAVLAAGFYKVI | | BOFUCK0952 | VAPIGIGFSLFIGHLVGIF | WIYWLGPALGSFLAAGLYLGL |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| BOFUCK0895 | AHINPAVTFANCIF | GYAINLARDFGPRLMS | | BOFUCK0917 | GLFNPAVTLGMVLV | GGSLNPARSFGPCVVS | | BOFUCK0923 | GLFNPAVTLALAIL | GASLNPARSFGPSAIV | | BOFUCK0939 | GHFNAAVTISCAVW | -IELNSSRDLGARIVA | | BOFUCK0940 | GLFNPAVTIALCLV | GGALNPARAFGAEVIG | | BOFUCK0952 | GQFNPAVTLALVLI | GAGINPARAFSPALIQ |
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