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MIPModDB |
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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
| Protein |
Helix 1 |
Helix 2 |
| 1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
| 1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
| 1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
| 1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
| 2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
| 2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
| ASCLAV0897 | VIREPLAEWLGTTIAMTLGLCAGFST | SFASLAPAWGFAFMIAIYMAGG | | ASCLAV0903 | HCREAFSEFFGTMILILFGDGVVAQV | NYQSISWGWGIGAMLGIYVSG- | | ASCLAV0906 | HHREALAEALAVFVQLTVGISVDLSV | NPNTTGWCWGFAAMMGIYISGG | | ASCLAV0933 | NMIAMVGEFVGTFLFLFFSYAGTQVS | ALLYSSLCFGFSLTVNVWAFYR |
| Protein |
Helix 3 |
Helix 4 |
| 1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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| 1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
| 1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
| 1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
| 2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
| 2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
| ASCLAV0897 | PAKKCVVYVLAQIVGAITAGGLAYA | PVTAFFNEFVGTAVLVATIMALG | | ASCLAV0903 | PWRKFPIYAIAQVLGAMCGAAIVYG | KTGQFFSEFVASSILMFMIFAIK | | ASCLAV0906 | PKRKIPSYFAAQFLGAFVAALAVYG | PATAFFNEFLGTLCLTVTVLALG | | ASCLAV0933 | PPIRGVLVFAAQIVGGIAAAGVVSA | ISQGLFIEMFLTAQLVFVIIMLA |
| Protein |
Helix 5 |
Helix 6 |
| 1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
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| 1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
| 1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
| 1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
| 2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
| 2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
| ASCLAV0897 | MQAFIVGIVISVLVLSLGY | WGPWAADIAGGLCGGFLYDLV | | ASCLAV0903 | LTPLALFFLIFGIGACFGW | WIPIVAPFLGCTFGGWLYDMF | | ASCLAV0906 | MNSLIIGFVVACLSMTFSY | YGPWAGSLTGAFVGAFLYDAM | | ASCLAV0933 | LAPVAIGLAFFVAEMIGDY | WIYWVGPLLGSLLACGFYTFL |
| Protein |
Loop B |
Loop E |
| 1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
| 1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
| 1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
| 1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
| 2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
| 2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
| ASCLAV0897 | GHLNPAITISMSVW | GGCFNGARDFGPRLVA | | ASCLAV0903 | AHINPAVTFANCVF | GYAINLARDFGPRLVS | | ASCLAV0906 | AHMNPTITLMLWFY | GAAFNPSRDFGPRLAL | | ASCLAV0933 | GLFNPSVTLALCLV | GGSLNPARSLGPDVIN |
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Last Updated:
Saturday, April 5, 2025
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Bioinformatics and Biomolecular Simulation Laboratory,
Department of Biological Sciences and Bioengineering,
Indian Institute of Technology,
Kanpur, INDIA-208016
Copyright (c) 2007 All rights reserved, IIT Kanpur
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