MIPModDB
 
STRUCTURE BASED ALIGNMENT
  A conserved positions at helix-helix interface     A Ar/R selectivity filter

Protein
Helix 1
Helix 2
1J4N
FWRAVVAEFLAMILFIFISIGSALGF
DNVKVSLAFGLSIATLAQSVGH
1FX8
LKGQCIAEFLGTGLLIFFGVGCVAAL
GQWEISVIWGLGVAMAIYLTAG
1RC2
MFRKLAAECFGTFWLVFGGCGSAVLA
GFAGVALAFGLTVLTMAFAVGH
1Z98
FWRAAIAEFIATLLFLYITVATVIGH
GLLGIAWAFGGMIFVLVYCTAG
2B60
FWRAIFAEFFATLFYVFFGLGASLRW
HVLQVALAFGLALATLVQAVGH
2F2B
LTKRCIAEFIGTFILVFFGAGSAAVT
DWVAIGLAFGFAIAASIYALGN
ARTHAL0001FLQKLIAEFLGTYFLVFTGCASVVVNTLPGIAIVWGLTIMVLIYSLGH
ARTHAL0002FLQKLMAEVLGTYFLIFAGCAAVAVNTLPGIAIVWGLTVMVLVYSLGH
ARTHAL0003FLQKLLAELVGTYYLIFAGCAAIAVNTLVGIAVVWGIVIMVLVYCLGH
ARTHAL0004FVQKLIGEFVGTFTMIFAGCSAIVVNTLPGIALVWGLVVTVMIYSIGH
ARTHAL0005LTQKLIAEMIGTYFIVFSGCGVVVVNTFPGICVTWGLIVMVMIYSTGH
ARTHAL0006LTQKLIAEMIGTYFIIFSGCGVVVVNTFPGICVTWGLIVMVMIYSTGH
ARTHAL0007LTRKLGAEFVGTFILIFTATAGPIVNTLIGNAACAGLAVMIIILSTGH
ARTHAL0008LYRKLGAEFVGTLILIFAGTATAIVNTLIGCAASAGLAVMIVILSTGH
ARTHAL0009PLRIVMAELVGTFILMFSVCGVISSTGLLEYAVTAGLSVVVVVYSIGH
ARTHAL0010FWRAGIAEFIATFLFLYITVLTVMGVGIQGIAWAFGGMIFALVYCTAG
ARTHAL0011FWRAGIAEFIATFLFLYITVLTVMGVGIQGIAWAFGGMIFALVYCTAG
ARTHAL0012FYRAGIAEFIATFLFLYITVLTVMGVGIQGIAWAFGGMIFALVYCTAG
ARTHAL0013FYRAGIAEFIATFLFLYITVLTVMGVGIQGIAWAFGGMIFALVYCTAG
ARTHAL0014FYRAGIAEFIATFLFLYVTVLTVMGVGIQGIAWAFGGMIFALVYCTAG
ARTHAL0015FYRAVIAEFVATLLFLYITVLTVIGYGILGIAWAFGGMIFILVYCTAG
ARTHAL0016LYRAVIAEFVATLLFLYITVLTVIGYGILGIAWAFGGMIFILVYCTAG
ARTHAL0017LYRAVIAEFVATLLFLYVTVLTVIGYGILGIAWAFGGMIFILVYCTAG
ARTHAL0018LYRAVIAEFVATLLFLYVSILTVIGYGILGIAWAFGGMIFVLVYCTAG
ARTHAL0019FYRALIAEFIATLLFLYVTIMTVIGYGVLGIAWAFGGMIFILVYCTAG
ARTHAL0020FYRAVIAEFIATLLFLYVTVLTVIGFGLLGISWAFGGMIFILVYCTAG
ARTHAL0021FYRALIAEFIATLLFLYVTVATVIGHGLLGIAWAFGGMIFVLVYCTAG
ARTHAL0022FYRAIIAEFIATLLFLYVTVATVIGHGLLGIAWAFGGMIFVLVYCTAG
ARTHAL0023VLKSAIGDMLMTFSWVVLSATFGIQTPLVILTSLIFVYVSIFTVIF--
ARTHAL0024AVKSALGDMVITFLWVILSATFGIQTPLVISTLVVFVSISIFTVIGNV
ARTHAL0025RIGLVVTDLVLSFMWIWAGVLVNILVGEIVRYLFSIISMFIFAYLQQA
ARTHAL0026ALKAALAEFISTLIFVVAGSGSGMAFGLVAAAVAHAFGLFVAVSVGAN
ARTHAL0027ALRAALAEFISTLIFVFAGSGSGIAFGLVAAALAHAFGLFVAVSVGAN
ARTHAL0028AIRAAFAEFFSMVIFVFAGQGSGMAYGLVAIAVCHGFALFVAVAIGAN
ARTHAL0029SLRAYLAEFISTLLFVFAGVGSAIAYGLVAIAVCHGFALFVAVAIGAN
ARTHAL0030SLKAYLSEFIATLLFVFAGVGSALAFGLVAVAVAHAFALFVGVSIAAN
ARTHAL0031SLKAYLSEFIATLLFVFAGVGSAVAFGLVAIAIAHAFALFVGVSIAAN
ARTHAL0032SIRATLAEFLSTFVFVFAAEGSILSLGLILVALAHAFALFAAVSAAIN
ARTHAL0033SIRATLAEFLSTFVFVFAGEGSILALGLVLVALAHALALFAAVSAAIN
ARTHAL0034CIKALIVEFITTFLFVFAGVGSAMATGLFAVAVAHAFVVAVMI-SAGH
ARTHAL0035ALRCYVSEFISTFFFVLAAVGSVMSSGVLIPAIANALALSSSVYISWN

Protein
Helix 3
Helix 4
1J4N
SVLRAIMYIIAQCVGAIVATAILSG
SGQGLGIEIIGTLQLVLCVLATT
1FX8
DKRKVIPFIVSQVAGAFCAAALVYG
FVQAFAVEMVITAILMGLILALT
1RC2
PAKEVVGYVIAQVVGGIVAAALLYL
MLSALVVELVLSAGFLLVIHGAT
1Z98
SLLRALVYMIAQCLGAICGVGLVKA
KGTALGAEIIGTFVLVYTVFSAT
2B60
SLLRAICYVVAQLLGAVAGAAVLYS
VGQATIVEIFLTLQFVLCIFATY
2F2B
PGREVVPYIIAQLLGAAFGSFIFLQ
YWQAMLAEVVGTFLLMITIMGIA
ARTHAL0001PLKQVPAYVISQVIGSTLAAATLRLDLQAFTMEFIVTFYLMFIISGVA
ARTHAL0002PLKQVPAYVISQVIGSTLAAATLRLNLQSFVIEFIITFYLMFVISGVA
ARTHAL0003PLNQVPAYITVQVIGSTLASATLRLDLQAFVMEFIITGFLMLVVCAVT
ARTHAL0004PFNQVPGYIAAQLLGSTLAAAVLRLNTTSFVMEFIATFNLMFVISAVA
ARTHAL0005PWHQVPLYIGAQFAGSLLASLTLRLPARALVAEIIISFLLMFVISGVA
ARTHAL0006PWYQVPLYIGAQLTGSLLASLTLRLSGQALVAEIIISFLLMFVISGVA
ARTHAL0007PWAHVPAYIAAQVSASICASFALKGLGQAFALEFIITFILLFVVTAVA
ARTHAL0008PWKHVPVYIGAQVMASVSAAFALKALSQAFALEFIISFNLMFVVTAVA
ARTHAL0009PWSQVPLYITAQTLGATAATLVGVSCVSAFFVELIATSIVVFLASALH
ARTHAL0010SLTRALYYIVMQCLGAICGAGVVKGKGSGLGAEIIGTFVLVYTVFSAT
ARTHAL0011SLTRAVYYIVMQCLGAICGAGVVKGKGSGLGAEIIGTFVLVYTVFSAT
ARTHAL0012SLTRAVFYIVMQCLGAICGAGVVKGKGSGLGAEIIGTFVLVYTVFSAT
ARTHAL0013SLTRAVFYMIMQCLGAICGAGVVKGKGSGLGAEIIGTFVLVYTVFSAT
ARTHAL0014SLTRALFYIVMQCLGAICGAGVVKGKGSGLGAEIVGTFVLVYTVFSAT
ARTHAL0015SLPRALLYIIAQCLGAICGVGFVKATGTGLAAEIIGTFVLVYTVFSAT
ARTHAL0016SLIRAVLYMVAQCLGAICGVGFVKATGTGLAAEIIGTFVLVYTVFSAT
ARTHAL0017SLIRAVLYMVAQCLGAICGVGFVKATGTGLAAEIIGTFVLVYTVFSAT
ARTHAL0018SLVRTVLYIVAQCLGAICGCGFVKAKGTGLGAEIIGTFVLVYTVFSAT
ARTHAL0019TLVRAVMYMVAQCLGAICGVALVKAIGTGVAAEIIGTFVLVYTVFSAT
ARTHAL0020SLVRAVSYMVAQCLGATCGVGLVKVVGVGVGAEIIGTFVLVYTVFSAT
ARTHAL0021SLVRALGYMIAQCLGAICGVGFVKAKGTALGAEIIGTFVLVYTVFSAT
ARTHAL0022SLPRAVAYMVAQCLGAICGVGLVKATGTALGAEIIGTFVLVYTVFSAT
ARTHAL0023TLFSLAIRLPAQAIGAAGGALAIMEVHTGAIAETILSFGITFAVLLII
ARTHAL0024SLFSLAIRSPAQAIGAAGGAITIMEAHNGAISEVVLSFSVTFLVLLII
ARTHAL0025FIFSVFVRIPVEVIGSILAVKHIIHIHHGALTEGILTFFIVLLSMGLT
ARTHAL0026TLLRGILYWIAQLLGSVVACLILKFVLNAFVFEIVMTFGLVYTVYATA
ARTHAL0027TLLRGILYWIAQLLGSVAACFLLSFSLNALVFEIVMTFGLVYTVYATA
ARTHAL0028TLLRAILYWIAQLLGAVVACLLLKVPWNAVVFEIVMTFGLVYTVYATA
ARTHAL0029TVITGVFYWIAQLLGSTAACFLLKYSIEGVVMEIIITFALVYTVYATA
ARTHAL0030TVITGFFYWIAQCLGSIVACLLLVFAIEGVVMEIVVTFALVYTVYATA
ARTHAL0031TLITGFFYWIAQCLGSIVACLLLVFAVEGVVMEIVVTFALVYTVYATA
ARTHAL0032TAIRAIYYWIAQLLGAILACLLLRLAVNGLVLEIILTFGLVYVVYSTL
ARTHAL0033SVIRAIYYWVAQLIGAILACLLLRLELHGLLMEIILTFALVYVVYSTA
ARTHAL0034SVFRAFLYWIDQLLASSAACFLLSYYTQGIIWEIILTFSLLFTVYATI
ARTHAL0035SVPTAMFYWTSQMIASVMACLVLKVGFGASVLEGVLAFVLVYTVFTAS

Protein
Helix 5
Helix 6
1J4N
SGPLAIGFSVALGHLLAID
WIFWVGPFIGAALAVLIYDFI
1FX8
LAPLLIGLLIAVIGASMGP
LVPLFGPIVGAIVGAFAYRKL
1RC2
FAPIAIGLALTLIHLISIP
WFFWVVPIVGGIIGGLIYRTL
1Z98
LAPLPIGFAVFMVHLATIP
WIFWVGPFIGAAVAAAYHQYV
2B60
SVALAVGFSLTLGHLFGMY
WVYWVGPVIGAGLGSLLYDFL
2F2B
FAGIIIGLTVAGIITTLGN
SIYVIGPIVGAVLAALTYQYL
ARTHAL0001LAGLAIGSTVLLNVLIAAPWIYLVAPTLGAIAGAWVYNTV
ARTHAL0002LAGLAVGSTVLLNVIIAGPWIYIVSPIVGAVSGAWVYNMV
ARTHAL0003LEGLIIGATVTLNVIFAGEWIYLLAPTLGAVSGALIHKML
ARTHAL0004FAGIAIGATIVLDILFSGPWLYIVSPVIGALSGAWTYGLL
ARTHAL0005LAGIAVGMTIMVNVFVAGPWVYIVGPVLGVISGGFVYNLI
ARTHAL0006LAGIAVGMTIILNVFVAGPWVYIVGPFVGIFAGGFVYNFM
ARTHAL0007LAGIAVGATVMLNILVAGPWVYLVAPTLGAISGAAVYTGV
ARTHAL0008LAGIAVGATVMLNILIAGPWVYLTAPILGALIGAGTYTIV
ARTHAL0009LTGFVIGTVISLGVLITGPWIYMTAPVIGAIIAVLTYRSI
ARTHAL0010LAPLPIGFAVFLVHLATIPWVFWVGPFIGAALAALYHVVV
ARTHAL0011LAPLPIGFAVFLVHLATIPWVFWVGPFIGAALAALYHVIV
ARTHAL0012LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAALYHQLV
ARTHAL0013LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAALYHQIV
ARTHAL0014LAPLPIGFAVFLVHLATIPWIFWVGPFIGAALAALYHQIV
ARTHAL0015LAPLPIGFAVFMVHLATIPWIFWVGPFIGAAIAAFYHQFV
ARTHAL0016LAPLPIGFAVFMVHLATIPWIFWVGPFIGAAIAAFYHQFV
ARTHAL0017LAPLPIGFAVFMVHLATIPWIFWVGPFIGATIAAFYHQFV
ARTHAL0018LAPLPIGFAVFMVHLATIPWIFWVGPMIGAAAAAFYHQFI
ARTHAL0019LAPLPIGFAVFIVHLATIPWIFWVGPFAGAAIAAFYHQFV
ARTHAL0020LAPLPIGFSVFMVHLATIPWIFWVGPFVGAAIAAFYHQFV
ARTHAL0021LAPLPIGFAVFMVHLATIPWIFWVGPFLGALAAAAYHQYI
ARTHAL0022LAPLPIGFAVFMVHLATIPWIFWVGPFVGALAAAAYHQYI
ARTHAL0023AKTFLLALATISFVVAGSKYVYWISSFVGALSSALLFRSI
ARTHAL0024AKTFLLALATVSVFVVGSKYVYWISSYTGAILAAMLFRII
ARTHAL0025MKTWIGSLAKLTLHILGSDLVYWLGPVKATLLAVWFFKVV
ARTHAL0026IAPIAIGFIVGANILAGGAWVYWAGPLVGGGIAGLIYEVF
ARTHAL0027IAPIAIGFIVGANILAGGAWVYWAGPLIGGGLAGIIYDFV
ARTHAL0028IAPLAIGLIVGANILVGGAWVYWVGPFIGAAIAAIVYDTI
ARTHAL0029IAPLAIGLIVGANILAAGPWVYWVGPLIGGGLAGLIYGNV
ARTHAL0030IAPIAIGFIVGANILAAGPWIYWVGPLVGGALAGLIYGDV
ARTHAL0031IAPIAIGFIVGANILAAGPWIYWVGPLVGGALAGLIYGDV
ARTHAL0032IAPLAIGLIVGANILVGGPWIYWVGPFIGSALAALIYEYM
ARTHAL0033IAPLAIGLIVGANILVGGPWIYWVGPFIGGALAALIYEYM
ARTHAL0034FGPLLTGFVVGANILAGGAWVYWVGPLIGGGLAGFIYENV
ARTHAL0035VGPIFIGFVAGANVLAAGPAVYWVGPLLGGATGALVYDNV

Protein
Loop B
Loop E
1J4N
AHLNPAVTLGLLLS
GCGINPARSFGSSVIT
1FX8
AHLNPAVTIALWLF
GFAMNPARDFGPKVFA
1RC2
GHFNPAVTIGLWAG
NTSVNPARSTAVAI-F
1Z98
GHINPAVTFGLFLA
GTGINPARSFGAAVIF
2B60
AHVNPAVTFAFLVG
GAGMNPARSFAPAILT
2F2B
CHINPAVTIGLWSV
GSSLNPARTFGPYLND
ARTHAL0001AHINPAVTIAFASCSASMNPGRSLGPALVY
ARTHAL0002AHFNPAVTIAF-ASGASMNPGRSLGPAMVY
ARTHAL0003AHFNPAVTLALASSGASMNPARSIGPALVW
ARTHAL0004AHFNPAVSIAFASSGASMNPARSLGPALIW
ARTHAL0005AHFNPAVTVTFAIFGASMNPARSLGPALVM
ARTHAL0006AHFNPAVTVTFAVFGASMNPARSLGPAIVM
ARTHAL0007AHLNPSLTIAFAALGGSMNPVRTLGPAVAS
ARTHAL0008AHLNPAVTIAFAALSASMNPVRTLGPAIAA
ARTHAL0009AHLNPSITIAFAVFGGSMNPARSLGPAVVA
ARTHAL0010GHINPAVTFGLFLAGTGINPARSLGAAIIY
ARTHAL0011GHINPAVTFGLFLAGTGINPARSLGAAIIF
ARTHAL0012GHINPAVTFGLFLAGTGINPARSLGAAIIY
ARTHAL0013GHINPAVTFGLFLAGTGINPARSLGAAIIY
ARTHAL0014GHINPAVTFGLFLAGTGINPARSLGAAIIY
ARTHAL0015GHINPAVTFGLFLAGTGINPARSFGAAVIY
ARTHAL0016GHINPAVTFGLFLAGTGINPARSFGAAVIY
ARTHAL0017GHINPAVTFGLFLAGTGINPARSFGAAVIF
ARTHAL0018GHINPAVTVGLFLAGTGINPARSFGAAVIY
ARTHAL0019GHINPAVTFGLLLAGTGINPARSLGAAIIY
ARTHAL0020GHINPAVTFGLFLAGTGINPARSFGAAVIY
ARTHAL0021GHINPAVTFGLFLAGTGINPARSFGAAVIY
ARTHAL0022GHINPAVTFGLFLAGTGINPARSFGAAVIY
ARTHAL0023ASFNPTGSAAFYVAGPAMNPAIAFGWAYMY
ARTHAL0024ASFNPCGNAAFYTARPFMNPAIAFGWAYIY
ARTHAL0025GLYNPLTALAAGVSGGCMNPAAVMGWAYAR
ARTHAL0026GHVNPAVTFGAFIGGASMNPAVAFGPAVVS
ARTHAL0027GHVNPAVTFGVLLGGASMNPAVAFGPAVVS
ARTHAL0028GHVNPAVTFGAFIGGASMNPAVSFGPAVVS
ARTHAL0029GHVNPAVTFGLAVGGGSMNPARSFGPAVAA
ARTHAL0030GHLNPAVTLGLAVGGGSMNPARSFGPAVVS
ARTHAL0031GHLNPAVTLGLAIGGGSMNPARSFGPAVVS
ARTHAL0032GHVNPAVTFGALVGGASMNPARAFGPALVG
ARTHAL0033GHVNPAVTFAALIGGASMNPARAFGPALVG
ARTHAL0034GHLNPAVTLGLLLGGASMNPARSFGPALVS
ARTHAL0035GHVNPAVTFAMAVAGGSMNPACAFGSAMVY
 
 
Last Updated:
Best Viewed at 1024X768 resolution on IE 5.0+, Firefox 2.0+

Bioinformatics and Biomolecular Simulation Laboratory, Department of Biological Sciences and Bioengineering,
Indian Institute of Technology, Kanpur, INDIA-208016
Copyright (c) 2007 All rights reserved, IIT Kanpur