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MIPModDB |
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STRUCTURE BASED ALIGNMENT |
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A conserved positions at helix-helix interface A
Ar/R selectivity filter
Protein |
Helix 1 |
Helix 2 |
1J4N |
FWRAVVAEFLAMILFIFISIGSALGF |
DNVKVSLAFGLSIATLAQSVGH |
1FX8 |
LKGQCIAEFLGTGLLIFFGVGCVAAL |
GQWEISVIWGLGVAMAIYLTAG |
1RC2 |
MFRKLAAECFGTFWLVFGGCGSAVLA |
GFAGVALAFGLTVLTMAFAVGH |
1Z98 |
FWRAAIAEFIATLLFLYITVATVIGH |
GLLGIAWAFGGMIFVLVYCTAG |
2B60 |
FWRAIFAEFFATLFYVFFGLGASLRW |
HVLQVALAFGLALATLVQAVGH |
2F2B |
LTKRCIAEFIGTFILVFFGAGSAAVT |
DWVAIGLAFGFAIAASIYALGN |
ANGAMB0293 | IWRMLVAEFLGTFFLVAIGIGSTTGW | TLTQIAFTFGLVVATLAQAFGH | ANGAMB0294 | LWRALLAEFVGTCIFILNFFACAACT | DKTLISLAFGLSVFMVVMSIGH | ANGAMB0295 | NISVFLAELIGTGLLVMLGCMGCVSG | SHFELCINFGLIVMIIVQIFGC | ANGAMB0296 | VFTLFLAEFFGTAMLLFGGCMASIDG | SNISRGITFGMVVMMAFITFSA |
Protein |
Helix 3 |
Helix 4 |
1J4N |
SVLRAIMYIIAQCVGAIVATAILSG |
SGQGLGIEIIGTLQLVLCVLATT
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1FX8 |
DKRKVIPFIVSQVAGAFCAAALVYG |
FVQAFAVEMVITAILMGLILALT |
1RC2 |
PAKEVVGYVIAQVVGGIVAAALLYL |
MLSALVVELVLSAGFLLVIHGAT |
1Z98 |
SLLRALVYMIAQCLGAICGVGLVKA |
KGTALGAEIIGTFVLVYTVFSAT |
2B60 |
SLLRAICYVVAQLLGAVAGAAVLYS |
VGQATIVEIFLTLQFVLCIFATY |
2F2B |
PGREVVPYIIAQLLGAAFGSFIFLQ |
YWQAMLAEVVGTFLLMITIMGIA |
ANGAMB0293 | SILKGAFYIVSQCIGAIAGAAVIKA | TGQGVLIEALITFMLVFVVHGVC | ANGAMB0294 | SLIRALMYVAAQCAGAVAATTALDV | DMQGLGFEFFLGFVLVLCVFGVC | ANGAMB0295 | TKVGALFLIFSQCIGAFMGYGILKL | NMQAVGIEFVATMVLILVCCGVW | ANGAMB0296 | SLQLTILYIVAQFAGALCGYGLLRA | SGMALAVEILLTGMLVWTNCGVW |
Protein |
Helix 5 |
Helix 6 |
1J4N |
SGPLAIGFSVALGHLLAID
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WIFWVGPFIGAALAVLIYDFI
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1FX8 |
LAPLLIGLLIAVIGASMGP |
LVPLFGPIVGAIVGAFAYRKL |
1RC2 |
FAPIAIGLALTLIHLISIP |
WFFWVVPIVGGIIGGLIYRTL |
1Z98 |
LAPLPIGFAVFMVHLATIP |
WIFWVGPFIGAAVAAAYHQYV |
2B60 |
SVALAVGFSLTLGHLFGMY |
WVYWVGPVIGAGLGSLLYDFL |
2F2B |
FAGIIIGLTVAGIITTLGN |
SIYVIGPIVGAVLAALTYQYL |
ANGAMB0293 | SAPLAIGLSITAGHLAAIK | WVYWVGPIVGGIVAGAVYRLF | ANGAMB0294 | VAPLAIGLTVTLGHLGVVE | WIYWAGPILGGVTAALLYCQL | ANGAMB0295 | SVALKFGFTVGALAVAAGP | WIYWVGPLGAAFLTAFAYKAV | ANGAMB0296 | SVPVKFAFLIAGLSIAGGP | WIYFAGPTIGSLLMVTIYRYI |
Protein |
Loop B |
Loop E |
1J4N |
AHLNPAVTLGLLLS |
GCGINPARSFGSSVIT |
1FX8 |
AHLNPAVTIALWLF |
GFAMNPARDFGPKVFA |
1RC2 |
GHFNPAVTIGLWAG |
NTSVNPARSTAVAI-F |
1Z98 |
GHINPAVTFGLFLA |
GTGINPARSFGAAVIF |
2B60 |
AHVNPAVTFAFLVG |
GAGMNPARSFAPAILT |
2F2B |
CHINPAVTIGLWSV |
GSSLNPARTFGPYLND |
ANGAMB0293 | CHINPAVTIGLIVT | GASMNPARSFGPAVVM | ANGAMB0294 | GHINPAVTAGMLAA | GSSMNPARSFGTAFVT | ANGAMB0295 | SHLNPAVTAAAWVY | GASMNPARSLGPVLWN | ANGAMB0296 | AIINPVVSLAAYIF | GASMNPARSLAPAIWN |
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Last Updated:
Thursday, January 2, 2025
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Bioinformatics and Biomolecular Simulation Laboratory,
Department of Biological Sciences and Bioengineering,
Indian Institute of Technology,
Kanpur, INDIA-208016
Copyright (c) 2007 All rights reserved, IIT Kanpur
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